Project Description:
This project was on how proteins are created. This process is known as protein synthesis where DNA is copied to make a polypeptide chain of amino acids. These amino acids then fold on top of each other to make proteins. In this process however the copying can make mutations which lead to the wrong protein being formed. In many cases this can lead to disease. For this project, Huntington disease was the focus.
Content:
Protein synthesis process:
1) Transcription: DNA being copied to the mRNA in the Nucleus.
2)Translation: mRNA being matched with tRNA to form a polypeptide chain
3) Protein folding: The polypeptide chain folding through 4 phases to make the final protein.
Key Terms:
Codon: A series of 3 Nucleotide bases that are in DNA And RNA.
Anti codon: A series of 3 Nucleotide bases that are copied onto mRNA.
Polymerase: An enzyme that forms the basic structure for DNA and RNA.
Proteins: A basic building block for cells and anything in the body.
mRNA: A type of RNA that carries copies of the DNA from the Nucleus to the ribosomes.
tRNA: Carries amino acids to the mRNA in the ribosome to form polypeptide chains.
Protein folding steps:
Primary Structure: The poly peptide chain.
Secondary Structure: The poly peptide chain moving to the Rough ER to form Beta sheets or Alpha Helix.
Tertiary Structure: Then the sheets or helix fold into a hydrophobic or philiclayes.
Quaternary: Everything comes together folding and domains to make the final protein.
Hydrophobic: rebeals water.
Hydrophilic: attract water.
Alpha Helix: One of the structures that form during the process of protein folding.
Beta Sheet: One of the structures that form during the process of protein folding.
Transcription: The first step in protein synthesis when DNA goes to RNA.
Translation: The second step in protein synthesis when RNA becomes a protein.
1) Transcription: DNA being copied to the mRNA in the Nucleus.
2)Translation: mRNA being matched with tRNA to form a polypeptide chain
3) Protein folding: The polypeptide chain folding through 4 phases to make the final protein.
Key Terms:
Codon: A series of 3 Nucleotide bases that are in DNA And RNA.
Anti codon: A series of 3 Nucleotide bases that are copied onto mRNA.
Polymerase: An enzyme that forms the basic structure for DNA and RNA.
Proteins: A basic building block for cells and anything in the body.
mRNA: A type of RNA that carries copies of the DNA from the Nucleus to the ribosomes.
tRNA: Carries amino acids to the mRNA in the ribosome to form polypeptide chains.
Protein folding steps:
Primary Structure: The poly peptide chain.
Secondary Structure: The poly peptide chain moving to the Rough ER to form Beta sheets or Alpha Helix.
Tertiary Structure: Then the sheets or helix fold into a hydrophobic or philiclayes.
Quaternary: Everything comes together folding and domains to make the final protein.
Hydrophobic: rebeals water.
Hydrophilic: attract water.
Alpha Helix: One of the structures that form during the process of protein folding.
Beta Sheet: One of the structures that form during the process of protein folding.
Transcription: The first step in protein synthesis when DNA goes to RNA.
Translation: The second step in protein synthesis when RNA becomes a protein.
Reflection
At first the concept of protein synthesis was hard to grasp but then over time the process came familiar. My first high point for the project was contributing to help draw the poster since this is not really my strong suit. The second was doing almost half of the groups research since we lost one of our group members half way through the project. During the project I also had some short comings. One of them was not including everyone's ideas in our final product. This lead to some personal tension between group members which I would like to avoid in the future. A seconded short coming was not staying focus 100% of the time. In the future I would like to avoid wandering the classroom being distracted and focus on better work.